Vitamin D Could Reduce Pancreatic Cancer Risk
Sunday, October 15th, 2006More recent evidence of the importance of vitamin D in this study that shows higher intakes of the vitamin are associated with significantly lower risk of pancreatic cancer in both men and women. Although the large-scale study is one of the first to closely look at that relationship, the results shouldn’t be too surprising.
Sunshine is the primary source of vitamin D for most people. The sun’s UVB rays hit the exposed skin and convert a molecule there into a different molecule (cholecalciferol, or vitamin D3), which is then converted in a couple of steps in the body into the active form of vitamin D.
Here’s an interesting site discussing the effects of sunlight and vitamin D deficiency on chronic disease:
The site includes some neat maps that show cancer mortality maps and average UVB exposure. Cancer rates clearly increase the farther north one lives. The evidence is strongest for breast, colon, ovarian, and prostate cancer. (Multiple sclerosis, hypertension, type 1 diabetes, cardiovascular disease, and rheumatoid arthritis, too).
The site also has a good position paper overview:
http://www.sunarc.org/evidencevitd.htm
With the change in seasons and the inability in the winter time to get sunshine in latitudes above 40 degrees (basically, anywhere north of San Francisco, Denver, Washington DC, etc.) strong enough to produce vitamin D, the importance of supplementation increases. Cholecalciferol is the form of vitamin D supplement you want to look for. It’s very inexpensive and widely available.
Since vitamin D is fat-soluble, it can be toxic at high levels. However, leading nutrition researchers agree that the current suggested intake levels from all sources (diet and sunshine) of 400 to 600 IU per day for adults are likely far below optimal. Recent research suggests that a total daily intake level of closer to 2000 IU is probably much more desired for otherwise healthy people.
(For comparison sake, someone at the beach in a swimsuit in mid-day summer sun generates about 10,000 IU of cholecalciferol in 15 minutes.)


